MD Anderson Cancer Center - Peking Union Medical College Hospital Joint Expert Video Second Opinion: Ovarian Cancer Cases and Application Guides
- Medebound HEALTH
- Sep 18
- 7 min read
Updated: Oct 21
A Case of Rare Ovarian Yolk Sac Tumor Recurrence and the Application of International Video Consultation Services
Author: Medical Editor Iris
Type: Case Report
Content:
Introduction
Rare tumors represent one of the most difficult challenges in oncology, often leaving both patients and physicians with limited options and great uncertainty. This case study highlights a collaborative effort between the rare ovarian tumor specialists of MD Anderson Cancer Center in the United States and the gynecologic oncology surgery team at Peking Union Medical College Hospital (PUMCH) in China.
Through the facilitation of Medebound HEALTH, an international medical services provider, a patient with recurrent ovarian yolk sac carcinoma was able to access a cross-border expert video consultation. The outcome offered not only a curative treatment plan but also renewed hope for the patient and her family.
Patient Profile
Name: Ms. Lin (pseudonym)
Age: 33 years
Chief concern: Seeking a second opinion from an MD Anderson expert in the U.S.
Primary treating hospital in China: Peking Union Medical College Hospital
Initial diagnosis: Yolk sac carcinoma (ovarian germ cell tumor)
Current condition: Recurrence of tumor after three surgeries and six rounds of chemotherapy
Disease Background
Ovarian yolk sac carcinoma is a rare malignant germ cell tumor arising from primitive yolk sac cells. It primarily affects young women, typically between 10–30 years of age. While the exact cause remains unclear, research suggests associations with:
Genetic mutations
Chromosomal abnormalities
Hereditary cancer syndromes (e.g., Swyer syndrome)
The disease is aggressive and recurrence rates remain high, especially when standard treatment options—surgery, chemotherapy, and radiotherapy fail to achieve lasting remission.
Domestic Treatment Journey
At PUMCH, Ms. Lin was under the care of Professor Yang,(pseudonym) a leading ovarian cancer specialist recognized across Asia. Despite undergoing extensive treatment including surgery, radiotherapy, and chemotherapy the cancer recurred, localized to the same pelvic region.
Recognizing the limitations of available options in China, Professor Yang recommended consulting international experts. He had previously met specialists from MD Anderson Cancer Center, a globally renowned institution for cancer care. However, direct outreach attempts to MD Anderson were unsuccessful.
At this stage, Ms. Lin and her family turned to Medebound HEALTH, a professional service specializing in connecting Chinese patients with top U.S. cancer centers.
International Coordination and Consultation Setup
Upon receiving the request, Medebound HEALTH:
Carefully reviewed and translated Ms. Lin’s medical records.
Matched her case with the MD Anderson Chief of Internal Medicine in Gynecologic Oncology, a top expert in rare ovarian cancers.
Successfully secured a video consultation appointment within one week, overcoming institutional barriers that normally prevent direct requests from individual patients.
On May 16, 2023, at 8:00 PM Beijing time, the video consultation took place. Professor Yang and his medical team were invited to join the session alongside the patient and her family.
Consultation Details
Before the consultation, the Medebound HEALTH team helped Ms. Lin prepare by:
Organizing her complete medical history
Translating clinical notes into English
Drafting key medical questions for the U.S. specialist
During the consultation, MD Anderson experts thoroughly reviewed the case, including Ms. Lin’s prior treatments and test results. Additional imaging—PET/CT scans from a top Chinese hospital—was requested to confirm disease progression.
Expert Assessment and Recommendations
Targeted & Immunotherapy Options: Currently unsuitable, as Ms. Lin’s tumor lacked targetable genetic mutations.
Surgical Resection: Considered but ultimately ruled out due to prior radiation in the region and the small size/location of the recurrent nodule.
Curative Proposal: High-dose chemotherapy combined with autologous stem cell transplantation.
Estimated cure rate: 30–50%, potentially higher in young patients.
Not widely available in China; only a limited number of U.S. institutions have extensive experience with this approach.
Suggested chemotherapy regimen: high-dose etoposide plus carboplatin.
Recommendation: Immediate consultation with a U.S.-based stem cell transplant team.
This represented the most promising treatment option available to Ms. Lin.
Outcome and Patient Response
Following the consultation, Medebound HEALTH delivered a bilingual written report (Chinese and English) summarizing the expert’s findings and recommendations.
Ms. Lin(alias) and her family expressed great satisfaction with both the professionalism of the medical experts and the efficiency of Meten’s coordination. They carefully considered the treatment plan and costs, ultimately exploring the possibility of traveling abroad for care.
Patient’s feedback: “The team demonstrated solid expertise, sincere service, and outstanding efficiency. The consultation perfectly met our expectations. We are very grateful.”
Institutional Background
MD Anderson Cancer Center
Founded: 1941
Location: Houston, Texas, USA
Designation: One of the first Comprehensive Cancer Centers under the U.S. Cancer Act of 1971
Recognition: Accredited by 39 medical oncology societies; consistently ranked #1 in cancer care in the U.S.
Medebound HEATH
Expertise: With over 8 years of international oncology service experience, Medebound HEALTH has successfully helped patients with complex and rare conditions access world-class cancer specialists in the United States.
Our Services Include:
Preparation and professional translation of international medical reports
Fast, accurate matching and scheduling of overseas expert video consultations
Full assistance with visa applications for patients traveling abroad
Coordination with U.S. hospitals to access the latest cancer treatments
Seamless communication between Chinese and U.S. medical teams
Conclusion
This case underscores the importance of international collaboration in treating rare and aggressive cancers. For Ms. Lin, access to MD Anderson’s expertise opened new avenues for potentially curative treatment when local options had been exhausted.
As global oncology advances, platforms like Meten Medical play a vital role in bridging gaps between patients and leading international experts bringing timely, innovative treatments within reach.
One more medical opinion means one more chance for hope.
Application for MD Anderson Video Consultation
Ordinarily, MD Anderson physicians do not directly accept requests for international video consultations. Through Meten Medical’s extensive U.S. medical network, however,International patients can access this service, subject to institutional approval and availability.
Note: Consultations are limited and involve significant costs. Medebound HEALTH assists in navigating applications, coordinating with physicians, and ensuring smooth communication and follow-up.
About Medebound HEALTH: Since 2016, we've helped thousands of affluent families mostly from Asia get personalized cancer remote second opinions from the top 1% of US hospitals through simple written opinion or video calls. These are the same top doctors trained or active at top hospitals such as MD Anderson, Mayo Clinic, Memorial Sloan Kettering and Johns Hopkins, etc, you will get their expertise, their treatment suggestion, and their guidance - all from your home. No matter where you live, world-class cancer care is just a few steps away.
Why Choose Medebound HEALTH for International Cancer Care and Second Opinions
Trusted Expertise, Faster Access, and Comprehensive Support Beyond Hospital International Departments
Efficiency Advantage: Compared with contacting hospital international departments directly, Medebound HEALTH ensures a much smoother and faster process:
Written or video second opinions: arranged within 1–2 weeks
On-site appointments: arranged within 3–4 weeks
Comprehensive support services: While hospital international departments typically provide only medical translation, Medebound HEALTH goes further by offering daily life translation, logistical assistance, and personalized care support ensuring patients and families feel fully supported throughout their treatment journey.
Important Considerations:
Insurance Coverage: Check with your insurance provider regarding coverage for second opinion consultations, as many may not cover the cost.
Second Opinion Limitation: U.S. second opinion consultations are for reference purposes only. The physician-patient relationship is not formed with your remote physician. Remote consultations differ from in-person visits and are subject to limitations due to lack of direct in-person examination. As such you will need to understand Medebound HEALTH and the U.S. doctor are not liable for any treatment decisions made based on the second opinion, and accept the risks of relying on any information provided under this agreement. You will need to sign an agreement to confirm that you voluntarily request this service and understand its limitations.
Timeliness: Getting a second opinion early in your treatment journey, ideally before starting treatment, can be beneficial
Frequently Asked Questions (FAQ): All Answers You Need to Know
What exactly is a yolk sac tumor, and why is it so challenging?
A yolk sac tumor is a rare and aggressive form of ovarian cancer, most often affecting younger women. It grows rapidly and frequently recurs even after treatment. Because it’s uncommon, many hospitals have limited experience managing it, making optimal treatment difficult.
Standard therapies may not always work, so accessing international expertise can reveal advanced, life-saving options.
Takeaway: Yolk sac tumors demand specialized, timely care guided by experienced experts.
Result: Patients gain access to a wider range of advanced therapies worldwide.
How can I get an international second opinion for cancer through Medebound HEALTH?
With Medebound HEALTH, you can request a secure video consultation or written second opinion from top U.S. hospitals such as MD Anderson, Mayo Clinic, or Memorial Sloan Kettering—without traveling.
Our team collects and translates your records, matches you with the right specialist, and arranges your consultation within 1–2 weeks.
Why do cancer patients use Medebound HEALTH for second opinions?
Patients turn to Medebound HEALTH when they want expert confirmation of their diagnosis, access to newer treatment options, or guidance on complex or rare cancers.
We simplify everything—medical record collection, expert coordination, and follow-up—so patients can focus on healing while gaining global-level medical insight.
What advanced cancer treatments might I learn about through a Medebound HEALTH consultation?
U.S. experts may recommend therapies not yet available in your country—like high-dose chemotherapy with stem cell transplant, immunotherapy, or targeted precision medicine.
Medebound HEALTH ensures you understand these options and how they compare to your current treatment.
Does Medebound HEALTH replace my local doctor?
No. Your local doctor remains in charge of your ongoing care.
Medebound HEALTH connects you to international experts who provide advice and treatment recommendations that complement your local plan. You keep your current care team but gain powerful new insights.
How fast can I schedule a video consultation with Medebound HEALTH?
Most consultations are arranged within 1–2 weeks after you share your medical records.
Medebound HEALTH fast-tracks urgent cancer cases so you receive expert opinions quickly—because timing matters in cancer care.
Does insurance cover Medebound HEALTH’s second opinion services?
Some insurance plans may cover part of the cost for international consultations. Others may not.
Even when not covered, families often see a Medebound HEALTH second opinion as a worthwhile investment that prevents unnecessary treatments and helps ensure the right medical path from the start
Contact Us to Get Started
Email: support@medeboundhealth.com
Website: www.medeboundhealth.com
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Submit your case today and connect with MD Anderson experts through Medebound HEALTH.
Disclaimer
We strive to maintain the accuracy and provide regular updates for the treatment information described in this article. However, treatment outcomes may vary between individuals. The information provided here is not intended as a diagnostic or treatment recommendation and should not replace the careful evaluation and advice of your attending physician
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