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Video Second Opinion with MD Anderson Professor for Advanced Pancreatic Cancer Patient Prior to American Medical Travel


Author: Medical Editor Iris

Type: Real Case


Content:




Introduction

This case describes the journey of Ms. Zhang (pseudonym), a 55-year-old female patient diagnosed with advanced pancreatic ductal adenocarcinoma with lung metastasis. Facing limited options in Asia, she urgently sought access to U.S. clinical trials and became a leading expert at the MD Anderson Cancer Center (MDACC) in Houston, Texas.


Through the support of Medebound HEALTH, Ms. Zhang received a high-level remote consultation with the Director of Gastrointestinal Oncology at MDACC. This consultation provided not only cutting-edge medical advice but also secured her enrollment pathway into potential clinical trials and confirmed the professor’s commitment to serve as her primary attending physician upon arrival in the United States.


Patient Profile

  • Patient: Ms. Zhang (pseudonym)

  • Age: 55 years

  • Diagnosis: Advanced pancreatic cancer with lung metastasis

  • Initial Detection: April 2021


Important Medical History:

  • April 2021: Elevated CA19-9, PET/CT revealed a mass in the pancreatic body, highly suspicious for malignancy.

  • April 2021: Underwent robotic minimally invasive pancreatic body resection.

  • Pathology: Ductal adenocarcinoma; no vascular invasion.

  • Genetic Findings: KRAS G12V mutation, PD-L1 expression (80% of tumor cells), and other pathogenic alterations.


Postoperative Treatments:


  • Chemotherapy cycles: Gemcitabine + paclitaxel + tislelizumab initially.

  • Later switched to regimens involving capecitabine, oxaliplatin, and 5-fluorouracil (5-FU) due to disease progression.


Key Clinical Question

Although Ms. Zhang and her family had already confirmed treatment appointments at MDACC, they wanted to ensure:


  1. Access to pancreatic cancer clinical trials in the U.S.

  2. A chance to engage directly with a leading pancreatic cancer expert at MDACC.

  3. Clarification of the latest global treatment options beyond conventional chemotherapy.


This led them to seek remote tele-consultation services with Medeboud HEALTH


Remote Consultation Process

  • Mode: Video consultation

  • Expert: Director of the Digestive System Oncology Department, MDACC (pancreatic cancer specialist)

  • Language: English (no translator required; patient’s family communicated fluently)


Unexpected Scheduling Issue

Originally, the professor’s schedule had to be adjusted due to an emergency, risking cancellation. However, thanks to contingency planning by Medeboud HEALTH the consultation was successfully maintained, demonstrating strong physician commitment.






Virtual video consultation between pancreatic cancer patient and MD Anderson oncology professor arranged by Medebound HEALTH. Photos and names are anonymized to protect patient's privacy and  confidentiality
Virtual video consultation between pancreatic cancer patient and MD Anderson oncology professor arranged by Medebound HEALTH. Photos and names are anonymized to protect patient's privacy and  confidentiality

Consultation Content


1. Clinical Assessment

  • Comprehensive review of medical history and treatment journey.

  • Reassurance provided: patients with lung metastases often have relatively better prognosis than those with liver or peritoneal spread.

  • Current regimen of gemcitabine, albumin-bound paclitaxel, and fluorouracil noted to be stabilizing disease.

  • However, no superior second-line regimens were identified, strengthening the case for trial participation.


2. Clinical Trial Opportunities

The professor introduced several ongoing and upcoming U.S. and international clinical trials:


  • KRAS-targeted therapies:

    • Revolution Medicine’s RMC-6236.

    • Mirati’s KRAS-directed trials.

    • Noted long wait times (several months).


  • MEK inhibitors and Immunotherapy combinations:

    • CTLA-4 inhibitors combined with PD-1/PD-L1 blockade.

    • While pancreatic cancer generally shows weak immunotherapy responses, select patients may benefit.


  • Personalized cancer vaccines:

    • Particularly mRNA-based vaccines.

    • More effective in post-surgical maintenance rather than in active metastatic disease.

    • Future applicability uncertain for KRAS G12D subtype.


International clinical trials:

  • Suggested exploring programs in Asia  for faster accessibility.


3. Specialist Commitments

  • Professor agreed to serve as primary attending physician for Ms. Zhang upon arrival at MDACC.

  • Offered to assist in clinical trial enrollment at MDACC.

  • Promised to deliver a follow-up written report within 24 hours after the consultation.


Comparison Before and After Consultation


Before:

  • The patient had confirmed an outpatient appointment at MDACC, but was assigned only an associate professor as attending physician.

  • Unclear which trials were suitable or accessible.


After:

  • The chief professor agreed to personally serve as attending physician.

  • Received detailed review of current and upcoming clinical trials.

  • Clarified options for KRAS-targeted drugs, immunotherapy, and vaccines.

  • Patients gained structured support and reassurance ahead of U.S. treatment.


Patient and Family Feedback

  • Expressed high satisfaction with the consultation quality.

  • Appreciated direct communication in English with the professor.

  • Valued timely follow-up report delivered by Medeboud HEALTH staff.

  • Confirmed the consultation provided new hope and concrete treatment direction.


Patient feedback
Patient Real Feedback


Feedback
Patient Real Feedback

Broader Context:  Why Remote Consultation Matters


Why Remote Consultation Matters

  • Cost Savings: Avoids unnecessary travel (savings up to 1M RMB across treatment journey).

  • Convenience: Access to global experts while staying at home.

  • Faster Access: Shortened waiting time (from 6 weeks to ~7 days).

  • Continuity of Care: Smooth transition from teleconsultation to in-person treatment.


Institutional Background


MD Anderson Cancer Center

  • Established in 1941, based in Houston, Texas.

  • Leading U.S. cancer hospital, consistently ranked #1 nationwide.

  • Accredited by 39 medical oncology societies.

  • Major global hub for cancer research, clinical trials, and treatment innovation.

Exterior view of MD Anderson Cancer Center in Houston, ranked top U.S. hospital for cancer care and research.
Md Anderson

Medebound HEALTH

About Medebound HEALTH: Since 2016, we've helped thousands of affluent families mostly from Asia get personalized cancer remote second opinions from the top 1% of US hospitals through simple written opinion or video calls.  These are the same top doctors trained or active at top hospitals such as MD Anderson, Mayo Clinic, Memorial Sloan Kettering and Johns Hopkins, etc, you will get their expertise, their treatment suggestion, and their guidance - all from your home. No matter where you live, world-class cancer care is just a few steps away.



How Medebound HEALTH Helps

Efficiency Advantage: Compared with contacting hospital international departments directly, Medebound HEALTH ensures a much smoother and faster process:


  • Written or video second opinions: arranged within 1–2 weeks

  • On-site appointments: arranged within 3–4 weeks

  • Comprehensive support services: While hospital international departments typically provide only medical translation, Medebound HEALTH goes further by offering daily life translation, logistical assistance, and personalized care support  ensuring patients and families feel fully supported throughout their treatment journey.


Important Considerations:

  • Insurance Coverage: Check with your insurance provider regarding coverage for second opinion consultations, as many may not cover the cost. 


  • Second Opinion Limitation: U.S. second opinion consultations are for reference purposes only. The physician-patient relationship is not formed with your remote physician. Remote consultations differ from in-person visits and are subject to limitations due to lack of direct in-person examination. As such you will need to understand Medebound HEALTH and the U.S. doctor are not liable for any treatment decisions made based on the second opinion, and accept the risks of relying on any information provided under this agreement. You will need to sign an agreement to confirm that you voluntarily request this service and understand its limitations.


  • Timeliness: Getting a second opinion early in your treatment journey, ideally before starting treatment, can be beneficial


Conclusion

This case illustrates how remote consultation, facilitated by Medeboud HEALTH, can transform the treatment journey for international patients with advanced cancer.

For Ms. Zhang, the video consultation with the MDACC professor:


  • Clarified global treatment options.

  • Secured direct access to a leading pancreatic cancer expert.

  • Opened doors to clinical trial enrollment.

  • Provided emotional reassurance and strategic guidance ahead of her U.S. trip.


Ultimately, the case demonstrates that timely teleconsultation can bridge the gap between local treatment limitations and global medical advances, offering patients new opportunities at a critical stage of illness.



Frequently Asked Questions (FAQ): All Answers You Need


1. What is a remote second opinion for advanced pancreatic cancer?

A remote second opinion lets patients consult world-class cancer experts without traveling abroad. It gives immediate access to top medical guidance directly from home.Through secure video calls or written reports, professors at MD Anderson review the patient’s case, explain treatment options, and outline clinical trial opportunities. This ensures patients receive leading insights before deciding on treatment or travel. 

Takeaway: Remote second opinions bridge the gap between local limitations and global expertise. They empower families to make informed decisions early.

 Result: Patients gain clarity, reassurance, and direction for their care. Families feel supported and confident about the treatment pathway ahead.


2. Why did Ms. Zhang seek a remote second opinion before traveling to the U.S.?

She wanted reassurance directly from a top professor before her U.S. visit. She also hoped to confirm clinical trial eligibility and advanced treatment options. Although she had an MD Anderson appointment booked, Ms. Zhang’s family requested a video consultation. This secured her access to the chief professor and provided confirmation of potential trial enrollment, giving her new confidence.

Takeaway: A remote consultation adds value even when travel is already arranged. It ensures patients connect with the right expert from the start.

 Result: Patients begin treatment better prepared, with fewer uncertainties. Families feel reassured that they are guided by leading global specialists.



3. What treatment challenges exist for advanced pancreatic cancer?

Pancreatic cancer progresses rapidly and often resists standard chemotherapy. Patients frequently face limited options after first-line regimens.

While regimens like gemcitabine plus paclitaxel may stabilize disease, they rarely achieve long-term control. That’s why newer strategies, including KRAS inhibitors, immunotherapy combinations, and personalized vaccines, are being tested in global clinical trials.

Takeaway: Standard therapy is rarely sufficient for advanced disease. Accessing innovative treatment options is critical for better outcomes.

Result: Patients benefit from remote consultations that open doors to international clinical trials. This brings hope beyond conventional treatments.


4. How did the MD Anderson professor assess Ms. Zhang’s case?

He carefully reviewed her treatment history and gave reassurance. He emphasized that clinical trial enrollment would be the best step forward.The professor explained that lung metastasis may have a slightly better outlook than liver spread. He noted that her regimen was controlling the disease but reinforced that only trials could provide truly new opportunities.

Takeaway: Expert assessment offers realistic yet hopeful guidance. It balances reassurance with strategic direction for treatment.

Result: Patients feel understood and supported by global experts. Families gain confidence knowing they are pursuing the most promising options.


5. What clinical trials were recommended in this case?

The professor recommended KRAS-targeted therapies, immunotherapy combinations, and personalized vaccines. These included both short- and long-term opportunities.Specific suggestions included Revolution Medicine’s RMC-6236, Mirati’s KRAS-directed studies, CTLA-4 plus PD-1 combinations, and mRNA-based vaccines. Some were immediately relevant, while others offered hope for future access. 

Takeaway: Clinical trials provide access to emerging treatments not yet available locally. They represent the frontier of pancreatic cancer care.

Result: Patients understand which trials are suitable and how to prepare. Families gain structured pathways to advanced therapies.


6. Can international patients access MD Anderson clinical trials?

Yes, international patients can enroll in MD Anderson clinical trials. However, eligibility and timing depend on strict trial requirements. While MD Anderson welcomes international patients, enrollment requires meeting inclusion criteria and may involve long waiting lists. Medebound HEALTH helps families identify suitable trials and prepare early for enrollment. 

Takeaway: Trial access is possible but requires preparation and guidance. Without support, opportunities may be missed. 

Result: Patients increase their chances of joining trials successfully. Families avoid delays and improve treatment planning.


7. How does Medebound HEALTH ensure smooth scheduling with top doctors?

Medebound HEALTH directly coordinates with professors and handles emergencies. This ensures consultations happen even under unexpected changes. In Ms. Zhang’s case, the professor’s schedule changed last-minute. Thanks to Medebound HEALTH’s planning, the consultation went ahead as promised, showing their ability to overcome scheduling challenges.

Takeaway: Strong coordination ensures patients don’t miss critical consultations. It reflects the reliability of professional facilitation.

Result: Patients gain secure access to high-demand doctors. Families avoid stress and delays during urgent times.


8. What changed for Ms. Zhang after the consultation?

She secured the chief professor as her primary doctor. She also gained clarity on clinical trials suited to her condition. Before the consultation, she was assigned to an associate professor with unclear trial access. Afterward, she was under the professor’s care and had a clear strategy for KRAS-targeted and immunotherapy trials.Takeaway: Remote consultations can significantly improve access and outcomes. They elevate the level of care patients receive abroad.Result: Patients move forward with confidence, knowing they have top-level support. Families feel reassured by structured treatment pathways.


9. How quickly can a second opinion be arranged?

A video or written second opinion can usually be arranged within 1–2 weeks. This is much faster than contacting hospitals directly. Medebound HEALTH accelerates the process compared to hospital international offices, which often take months. For diseases like pancreatic cancer, where time is critical, this speed can make a life-saving difference.

Takeaway: Fast access to expert advice can change the treatment journey. Patients cannot afford long delays. 

Result: Families receive expert guidance in days, not months. This allows them to act while treatment windows are still open.


10. What language support is available?

Consultations are typically in English, but translation is fully available. Patients can choose their preferred language.Ms. Zhang’s family spoke fluent English, so no translator was required. For others, Medebound HEALTH provides professional medical interpreters to ensure smooth communication and accurate understanding.

Takeaway: Language barriers should never stop patients from accessing global care. Translation ensures clarity and trust.

Result: Families feel comfortable, supported, and confident in communication. Doctors and patients connect effectively despite language differences.


11. Does remote consultation form a doctor–patient relationship?

No, remote consultations are advisory only. They do not replace in-person treatment or legal medical care.Remote second opinions provide expert recommendations but are limited by the lack of physical examination. Decisions must be confirmed by local doctors or in-person U.S. visits. This protects both patients and physicians.

Takeaway: Second opinions guide but do not substitute official treatment. They are a critical reference point in decision-making.

Result: Patients get expert direction while understanding legal and medical limits. Families stay informed without confusion.


12. How much cost can be saved by starting with remote consultation?

 Remote consultations can save families significant costs, sometimes up to 1M RMB. They prevent unnecessary early travel and misaligned appointments. By clarifying treatment direction in advance, families avoid expensive hospital stays and travel that may not lead to useful care. Instead, they arrive in the U.S. with the right doctor and trial pathway confirmed.

Takeaway: Remote consultations optimize both financial and medical planning. They reduce waste and unnecessary stress.

Result: Families conserve resources while maximizing treatment opportunities. Patients benefit from more focused use of funds.


13. What makes MD Anderson Cancer Center unique?

MD Anderson is the top-ranked cancer hospital in the U.S. It is known for pioneering treatments and extensive clinical research. Founded in 1941, MD Anderson leads the world in cancer care, research, and innovation. For pancreatic cancer, it runs many frontline clinical trials, giving patients access to therapies years before standard approval.

Takeaway: MD Anderson sets the global benchmark for oncology excellence. Its leadership makes it the top choice for advanced cancer cases.

Result: Patients gain access to the most innovative therapies. Families feel assured they are receiving care from the very best.



14. How does Medebound HEALTH support families beyond medical care?

Medebound HEALTH provides full logistical, translation, and emotional support. Their services go beyond arranging medical consultations.Unlike hospital international offices that mainly handle scheduling, Medebound HEALTH offers daily life assistance, language support, and travel coordination. This ensures patients feel guided every step of the way.

Takeaway: True patient support requires care beyond medicine. Medebound HEALTH covers both medical and personal needs.

Result: Families experience a smoother and less stressful journey. Patients can focus on recovery instead of logistics.


15. When is the best time to seek a second opinion?

The best time is early in the treatment journey, ideally before starting new therapies. Acting early maximizes available options. Early consultations allow patients to explore global standards, confirm trial eligibility, and avoid treatments that may limit future opportunities. Waiting too long may close important doors. 

Takeaway: Timing is critical when seeking expert guidance. Early action ensures the widest range of options.

 Result: Patients benefit from better planning and trial access. Families feel reassured they are not missing critical opportunities.


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Submit your case today and connect with MD Anderson experts through Medebound HEALTH.


New Way of Health: When knowledge, care, and global access come together—hope follows. — Medebound HEALTH

Disclaimer

We strive to maintain the accuracy and provide regular updates for the treatment information described in this article. However, treatment outcomes may vary between individuals. The information provided here is not intended as a diagnostic or treatment recommendation and should not replace the careful evaluation and advice of your attending physician.


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